On our episode with Brian Kernighan, I asked him if there were ever a situation in which he would advise you start a new program in C today. His response:

I think probably unless you are in one of these resource-constrained environments, clearly, right upfront, that you’re going to be resource-constrained and the improvement of hardware isn’t gonna rescue you in the next couple of years, I would not start with C. I really wouldn’t. And then it depends what is your application.

As if on queue, StackOverflow blogger Marcin Pasinski has done a comparison between C and Go in the quintessential resource-constrained environment. Oddly enough, no mention of TinyGo in the piece, but otherwise a solid analysis.