Go 1.18 was a major release where we saw the introduction of generics into the language as well as other notables such as fuzzing and workspaces. With Go 1.19 slated to come out next month, one has to wonder what’s next. Are we in store to be blown away by new and major features like we saw in 1.18? Not exactly but there are still lots of improvements to be on the lookout for.

Joining Mat & Johnny to touch on some of the most interesting ones is Carl Johnson, himself a contributor to the 1.19 release.

Drausin Wulsin, Director of ML at Immunai, joins Daniel & Chris to talk about the role of AI in immunotherapy, and why it is proving to be the foremost approach in fighting cancer, autoimmune disease, and infectious diseases.

The large amount of high dimensional biological data that is available today, combined with advanced machine learning techniques, creates unique opportunities to push the boundaries of what is possible in biology.

To that end, Immunai has built the largest immune database called AMICA that contains tens of millions of cells. The company uses cutting-edge transfer learning techniques to transfer knowledge across different cell types, studies, and even species.

Rob Barnes (a.k.a. Devops Rob) and Rosemary Wang (author of Infrastructure as Code - Patterns & Practices) are joining us today to talk about infrastructure secrets.

What do Rosemary and Rob think about committing encrypted secrets into a repository? How do they suggest that we improve on storing secrets in LastPass? And if we were to choose HashiCorp Vault, what do we need to know?

Thank you Thomas Eckert for the intro. Thank you Nabeel Sulieman (ep. 46) & Kelsey Hightower (ep. 44) for your gentle nudges towards improving our infra secrets management.

While scaling up machine learning at Instacart, Montana Low and Lev Kokotov discovered just how much you can do with the Postgres database. They are building on that work with PostgresML, an extension to the database that lets you train and deploy models to make online predictions using only SQL. This is super practical discussion that you don’t want to miss!

Jen Looper from Web Dev for Beginners and Front-end Foxes joins Jerod and Ali to discuss the exciting (but also intimidating) prospect of getting in to web development in 2022! Where should you start? What technologies should you focus on? Is it better to go all-in on a framework or stick with the fundamentals? Stuff like that!

We finally did it! All our static files are served from AWS S3. This is the most significant improvement to our app’s architecture in years, and now we have unlocked the next level: multi-cloud. We talk about that at length, and how it fits in our 2022 setup. The TL;DR is that changelog.com will fly, both literally and figuratively.

We also address Steve’s comment that he left on our previous Kaizen episode - thanks Steve!

Towards the end, we talk about Gerhard’s new beginnings at Dagger, where he gets to work with a world-class team and build the next-gen CI/CD. That’s right, Gerhard is now walking the Ship It talk all day, every day. If you want to watch him code live, you can do so every Thursday, in our weekly community session.

Kaizen!

From MIT researchers who have an AI system that rapidly predicts how two proteins will attach, to Facebook’s first high-performance self-supervised algorithm that works for speech, vision, and text, Daniel and Chris survey the AI landscape for notable milestones in the application of AI in industry and research.

Amal and Nick load up on coffee for a not-so-vite (lame joke!) conversation with Evan You all about Vite – a batteries included next-generation frontend tooling library. Vite continues to push the ecosystem forward with even stronger defaults, super speedy local development workflows, and a highly extensible universal plugin API. Need we say more?!

Vincent Ambo –the person behind nixery.dev, tvl.fyi, and a former Google engineer– shares his take on monorepos, Nix, and fully declarative systems without any Flux, Argo or Kubernetes.

While the tooling is impressive, it’s the principles behind it that captivated Gerhard’s imagination. Vincent has a rather interesting take on the monorepository idea, including one change - one version - one deploy. There are a lot of interesting links in the show notes, including all the code that Vincent uses to manage infrastructure.

As a result of this conversation, Gerhard is running Nix on one of his Macs, and also started experimenting with his first NixOS production instance.

We’re celebrating our 200th episode with a crazy game of Gophers Say! Mat Ryer hosts two epic teams including Go Time OGs Carlisia, Erik, and Brian!

How did we get from symbolic AI to deep learning models that help you write code (i.e., GitHub and OpenAI’s new Copilot)? That’s what Chris and Daniel discuss in this episode about the history and future of deep learning (with some help from an article recently published in ACM and written by the luminaries of deep learning).

Nhung Ho joins Daniel and Chris to discuss how data science creates insights into financial operations and economic conditions. They delve into topics ranging from predictive forecasting to aid small businesses, to learning about the economic fallout from the COVID-19 Pandemic.

Mireille and Adam discuss the process of forming memories, the various types of memory, anxieties, phobias, panic attacks, and how our attention and our memory relates to learning. Where you place your attention influences what you might remember. What you are able to remember influences how you feel, the choices you make, and your future outcomes.

In the wake of the coronavirus outbreak being declared a global pandemic and a national emergency here in the United States as well as many other countries around the world, it would be extremely difficult to have a serious conversation here on Brain Science that’s not colored by today’s very serious events. Mireille and Adam discuss the anxiety, fear, and panic that many may be facing. How do we navigate the unseeable unknown? How should we respond to change and the state of the world we are now living in?

Don’t panic. Prepare for change. Be adaptable. Be resilient.

Interfaces are everywhere in Go. The basic error type is an interface, writing with the fmt package means you are probably using an interface, and there are countless other instances where they pop up. In this episode Mark, Mat, Johnny, and Jon discuss interfaces at length, exploring what they are, how they are using them in their own projects, as well as tips for how you can leverage them in your own code.

Chris and Daniel talk with Greg Allen, Chief of Strategy and Communications at the U.S. Department of Defense (DoD) Joint Artificial Intelligence Center (JAIC). The mission of the JAIC is “to seize upon the transformative potential of artificial intelligence technology for the benefit of America’s national security… The JAIC is the official focal point of the DoD AI Strategy.” So if you want to understand how the U.S. military thinks about artificial intelligence, then this is the episode for you!

Go Time panelist Mat Ryer joins Jerod to talk through the pros and cons of GraphQL vs REST for a future Changelog API. There’s also a fair bit of language chat around Go and JavaScript, a section on Machine Learning, and some inside baseball on where Go Time is heading.

We’re talking with Sherol Chen, a machine learning developer, about AI at Google and AutoML methods. Sherol explains how the various AI groups within Google work together and how AutoML fits into that puzzle. She also explains how to get started with AutoML step-by-step (this is “practical” AI after all).

Lynne Tye is the founder of Key Values, a platform where developers find engineering teams that share their values. To be more precise, Lynne is a solo-founder. She’s also a team of one. Lynne’s path to becoming a founder was anything but typical. She had plans to follow in her parent’s and sister’s footsteps to go into academia, and got two years into pursuing her PhD in Neuroscience before she made one of the best choices in her life — she quit. Lynne has mastered the art of quitting, at the right time of course, and she’s used that art as her secret weapon in her quest to become a founder.

This week we bend reality to expose the deceptions of deepfake videos. We talk about what they are, why they are so dangerous, and what you can do to detect and resist their insidious influence. In a political environment rife with distrust, disinformation, and conspiracy theories, deepfakes are being weaponized and proliferated as the latest form of state-sponsored information warfare. Join us for an episode scarier than your favorite horror movie, because this AI bogeyman is real!

Chris Coyier joins Suz and Jerod to continue the discussion on The Great Divide in front-end-land. We also use this as an opportunity to gush on how much CSS-Tricks has done for the community, get Chris’ perspective on the history of the website, and finish up by sharing some amazing Pens on CodePen.io.

Panelists Suz Hinton and Nick Nisi discuss TensorFlow.js and Machine Learning in JavaScript with special guest Paige Bailey, TensorFlow mom and developer Advocate for Google AI.

Adam, Jerod, and Tim get together to talk about Plex! Plex is a media server which allows you to store your movies, TV shows, music, photos, etc. Turns out, you can actually use it together with an antenna to watch live TV and DVR content. They chat about what has Adam so excited, the pros and cons (or as Adam said, “trade-offs”), and how to get started.

Suz, Nick, and KBall are joined by special guest Aimee Knight to talk about CSS, how it’s often trivialized and how that in turn affects the people who write it, what CSS in JS is, and how to get started with it.

Thirteen years ago, Ashley Baxter inherited the family insurance business when her Dad passed away. Even though she’s a talented photographer, and built a successful photography business, the insurance industry kept calling her name. Ashley talks about what excites her about insurance, the challenges of running a business, and how burnout forced her to focus.

Aaron Hnatiw joined the show to talk about being a security researcher, teaching application security with Go, and a deep dive on how engineers and developers can get started with infosec. Plus: white hat, black hat, red team, blue team…Aaron sorts it all out for us.

In this episode of The Future of Node series recorded at Node Interactive 2016 Adam talked with Mikeal Rogers about the backstory of Node over the past few years to get to where we are today. We talked about io.js (the fork of Node), what’s happened in the community and the code since that time frame, how The Node.js Foundation has helped to solidify the foundation on which the Node ecosystem is being built on, initiatives and focuses in the near future, and more.

In this episode of Spotlight recorded at OSCON London 2016, Jerod talked with Sid Sijbrandij (CEO of GitLab) who was recently on The Changelog discussing GitLab’s Master Plan and a new style of development they call “Conversational Development”, to talk about how they’re executing on that plan. We also discussed the recent controversy around GitLab and the removal (and subsequent reposting) of security research data. We enjoyed hearing how Sid turns everything in to an opportunity.

Welcome to the first Spotlight series recorded at OSCON London 2016. Jerod talked with Katrina Owen, an accomplished speaker, creator of the excellent coding practice and feedback site, Exercism.io, and the co-author of 99 Bottles of OOP. Have you ever heard the story of how Katrina went from anonymous developer to sharing a byline with Sandi Metz? She shared all the details during this face-to-face chat.

Nadia Eghbal and Mikeal Rogers kick off Season 1 of Request For Commits with a two part conversation with Karl Fogel — a software developer who has been active in open source since its inception.