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Practical AI Practical AI #188

AlphaFold is revolutionizing biology

AlphaFold is an AI system developed by DeepMind that predicts a protein’s 3D structure from its amino acid sequence. It regularly achieves accuracy competitive with experiment, and is accelerating research in nearly every field of biology. Daniel and Chris delve into protein folding, and explore the implications of this revolutionary and hugely impactful application of AI.

Founders Talk Founders Talk #91

Fireside chat with Jack Dorsey

Adam was invited by our friends at Square to interview Jack Dorsey as part of their annual developer conference called Square Unboxed. Jack Dorsey is one of the most prolific CEOs out there — he’s a hacker turned CEO and is often working at the very edge of what’s to come (at scale). Jack is focused on what the future has to offer, he’s considered an innovator by many. He’s also a Bitcoin maximalist and has positioned himself and Block long on Bitcoin.

What you’re about to hear is the fireside chat Adam had with Jack at Square Unboxed 2022. Jack and Adam discuss the vision Square has for the developer platform and why it’s so central to the company’s strategy.

Backstage Backstage #20

New Mac day!

We upgraded to the new MacBook Pro M1 Max and decided to share our first impressions of the new hardware, how we migrate data and settings from our old machines (or don’t), which apps were “instant installs” for each of us, which apps we’re trying to live without, and how we get our new machines set up for work and play. Nerd out with us!

Brain Science Brain Science #14

Memory and learning

Mireille and Adam discuss the process of forming memories, the various types of memory, anxieties, phobias, panic attacks, and how our attention and our memory relates to learning. Where you place your attention influences what you might remember. What you are able to remember influences how you feel, the choices you make, and your future outcomes.

The Changelog The Changelog #382

The developer's guide to content creation

Stephanie Morillo (content strategist and previously editor-in-chief of DigitalOcean and GitHub’s company blogs) wrote a book titled The Developer’s Guide to Content Creation — it’s a book for developers who want to consistently and confidently generate new ideas and publish high-quality technical content.

We talked with Stephanie about why developers should be writing and sharing their ideas, crafting a mission statement for your blog and thoughts on personal brand, her 4 step recipe for generating content ideas, as well as promotional and syndication strategies to consider for your developer blog.

The Changelog The Changelog #379

Good tech debt

Jon Thornton (Engineering Manager at Squarespace) joined the show to talk about tech debt by way of his post to the Squarespace engineering blog titled “3 Kinds of Good Tech Debt”. We talked through the concept of “good tech debt,” how to leverage it, how to manage it, who’s in charge of it, how it’s similar to ways we leverage financial debt, and how Squarespace uses tech debt to drive product development.

Go Time Go Time #94

Structuring your Go apps

Jon, Mat, Johnny, and special guest Cory LaNou discuss the ins and outs of structuring Go programs. Why is app structure so important? Why is it hard to structure Go apps? What happens if we get it wrong? Why do we confuse folder structures with application design? How should a new Go app be structured?

Founders Talk Founders Talk #60

Leading data-driven software teams and products

For the final show of 2018 I’m talking with Travis Kimmel, the CEO of GitPrime. Travis has spent years as an engineering manager. Travis’s mission at GitPrime is to bring crystal clear visibility into the software development process and bridge the communication gap between engineering and stakeholders. This communication gap is often an ongoing plague in product development lifecycle. We talked through focus, tech debt, leading teams, predictability, and more.

Away from Keyboard Away from Keyboard #0

Welcome to Away from Keyboard

Away from Keyboard is a new show from Changelog that talks to creative professionals about how they do what they do, where they started, and how they deal with the things that make us all humans. As exciting as our work can sometimes be, we all face burnout, a lack of motivation, mental and physical health issues, and more. While these are topics that can be difficult to talk about, our experiences shape who we are and teach us so many things. AFK is a show that explores the human side of creative work.

The Changelog The Changelog #205

A protocol for dying with Pieter Hintjens

Since airing this show, Pieter passed away due to his battle with a metastasis of bile duct cancer in both lungs. But rather than listen to this show with sadness, listen with a happy heart and let’s celebrate Pieter’s life, and what he has accomplished. Thank you Pieter from the bottom of our hearts for your time on this show and for all that you are. You are loved by us my friend. This show will forever be a very special show for us.

Pieter Hintjens is the creator of ZeroMQ and The Collective Code Construction Contract (C4), a writer of many books and protocols, as well as a developer with decades of building software and communities – he’s someone who’s given so much, and continues to give - even up until the time he is planning for his death.

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